EPTFE has a unique structure and performance, good biocompatibility, and is very suitable for organ repair and surgery. And with the advancement of medicine, the popularity of various difficult operations, and the improvement of people’s living standards, the demand for EPTFE products is increasing.
After mixing, grinding, molding, calendering, drying, stretching, sintering, the white, soft, elastic EPTFE products will be produced.
EPTFE has a unique structure and performance, good biocompatibility, and is very suitable for organ repair and surgery. And with the advancement of medicine, the popularity of various difficult operations, and the improvement of people’s living standards, the demand for EPTFE products is increasing.
After mixing, grinding, molding, calendering, drying, stretching, sintering, the white, soft, elastic EPTFE products will be produced.
1. The polymer products of PTFE in medical can be divided into 3 categories:
1.1. Products that directly enter the human body (permanent or temporary)
Polymer products that are permanently present in the organism are implants (artificial substitutes for tissues and organs). The temporary use includes catheters, drainage tubes, earpieces, filters, ventilation devices, etc. They are mainly used for the transportation of substances and gases, the filtration of media, etc..
1.2. Products for external use
PTFE polymers properties such as plasticity, lightness, firmness, tightness and elasticity, stability to corrosive media, electrical insulation, etc., are very important. These products include gloves, tourniquets, limb fixing devices, external sheaths for various diagnostic devices, etc..
1.3. Functional components of biochemical analysis and biochemical synthesis equipment, devices for cultivating, regenerating and propagating cells, tissues, etc.
2. Application of PTFE products in medical treatment
2.1 Application of expanded PTFE patch in the repair of an external abdominal hernia is the most common general surgical disease, and the vast majority is an inguinal hernia. Surgical treatment is a recognized cure. PTFE is a complete fluoride, and the specially treated expanded PTFE fiber can exhibit a porous structure and can be made into a soft, bendable, non-abrasive material. The biggest advantage of the expanded PTFE patch is its good flexibility. The forces in all directions are in a balanced state. It can be cut and covered as needed. It shows fiber continuity and a unique porous microstructure. The cells can infiltrate into it. It has good tissue compatibility, superior mechanical properties, light postoperative wound pain, small scar formation, and good comfort. It is an ideal material for tension-free hernia repair.
2.2. Clinical application of EPTFE in rhinoplasty
2.2.1. In rhinoplasty
For the deformity of the nose, tissue transplantation is often required to repair the defect. Autologous cartilage is still the most ideal transplant material, but there are shortcomings such as difficulty in obtaining materials, damage to the donor area, and unpredictable absorption of the graft material. Allogeneic materials have immune rejection reactions and are difficult to preserve, so it is difficult to be widely used in the clinic. Therefore, people are constantly looking for an ideal artificial transplantation material. In the domestic rhinoplasty, more artificial graft materials are used, including silicone rubber and hydroxyapatite.
2.2.2. Artificial graft material
The advantage of EPTFE as an artificial graft material is that it has good tissue compatibility, and at the same time has the characteristics of being able to brake in soft tissue and be easier to take out. EPTFE has special physicochemical properties. Its micropores are 30μ on average, which makes the tissue endogenous, which makes the implant brake and is accepted by the body’s defense system. Because the tissue is not endogenous, it is not difficult to remove the graft.
2.2.3. EPTFE non-reinforced patch
Due to its good flexibility can be used to repair local soft tissue depressions on the back or tip of the nose. The reinforced patch and the shaped back of the nose have both certain flexibility and a certain hardness. Therefore, it can be used as a graft with an increased dorsal nose.
2.2.4. In nasal tip plasty
Nasal septal cartilage has always been considered to be an ideal autologous graft material. The septal cartilage is straight, elastic, and has a certain strength, but the disadvantage is that the amount of tissue obtained is limited. Of the commonly used artificial graft materials, hydroxyapatite cannot be used for nose tip shaping. Silicone rubber has a relatively high discharge rate for nose tip shaping, especially trauma, and insufficient skin and soft tissue coverage will increase the possibility of discharge. The texture of the silicone rubber is too hard. If the support force at the tip of the nose is too large, it may cause ischemia of the skin at the tip of the nose. Long-term support may make the local skin thin or even rupture and the prosthesis is discharged. The reinforced patch of EPTFE is harder than the nasal septal cartilage but softer than silicone. Therefore, the reinforced patch of EPTFE can be used as a support for the tip of the nose and the small column of the nose, but its lack of elasticity is its deficiency. Compared with silicone rubber, EPTFE has the characteristics of allowing tissue endogenous, so as to avoid ischemia and rupture of the skin of the supporting point, so EPTFE is a good nose tip forming material.
2.2.5. In nasal tip plasty
The sculpting of the prosthesis is the key to surgical plasty. It has been reported that the prosthesis is transplanted into an umbrella shape during nose tip shaping. Our experience is that the prosthesis is carved into a small L-shaped short arm and thinned with vascular forceps, which will give the short arm enough support to achieve the support and bulge of the tip of the nose.
2.2.6 Artificial blood vessels
At present, this product is mainly used for femoral artery pseudoaneurysm vascular transplantation; aortic constriction segment resection (or repair) artificial blood vessel transplantation; bridging material for portal hypertension shunt; bridging of superior and inferior vena cava with right atrium; intestinal system The vein is bridged with the right atrium; hemodialysis, etc. More than 100 clinical applications have received good results. The longest use of time has reached more than 9 years.
2.2.7 Artificial trachea
It is used for patients with large area tracheal cartilage defects, tracheal collapse, and failure to form normal breathing of the lumen caused by war injuries, trauma, and laryngeal cancer surgery. man of. After 10 cases of clinical application in Changchun Hospital of Air Force and follow-up for 10 years, the survival rate was 100%.
2.2.8. Other applications
After lung resection, artificial materials are used to eliminate the residual cavity, and EPTFE is an ideal packing material at this stage. EPTFE patch and polypropylene patch are safe and effective for inguinal hernia implantation in the elderly, with fewer complications and lower recurrence rate than traditional implantation. Among them, EPTFE patch is better than polypropylene patch The tablets are more comfortable. The inflammatory reaction and foreign body reaction caused by EPTFE are small, and no adverse reaction is seen on the damaged wound surface, which can be used as a wound covering material.
Post time: Jun-21-2020